Home News Publications Members Links Contact

Recent Group News RSS/XML feed

Graphene Metallization of High-Stress Silicon Nitride Resonators for Electrical Integration (1 August 2013)

V.P. Aidga and R. Barton has recently published an article in Nano Letters using graphene as a cotaing for silicon nitride membranes to reduce quality factor.

Single-molecule analysis of combinatorial epigenomic states in normal and tumor cells (29 March 2013)

P.J. Murphy, C.B. Wallin, K. Szeto, and J. Benitez has recently published an article in PNAS describing an approach to simultaneously detect multiple epigenetic marks on a single-molecule level as well as locating specific gene marks in normal and cancer genomes.

Multiplexed microcolumn-based process for efficient selection of RNA aptamers (13 February 2013)

A new article has been published by D. R. Latulippe et al. in the Analytical Chemistry. The article introduced a high throughput reusable SELEX microcolumn device optimized for multiplex aptamer selections. Both the process and device was demonstrated upon GFP-binding RNA aptamers and later used to perform a multiplex selection to heat shock factor proteins hHSF1 and hHSF2.

Preservation of Antibody Selectivity on Graphene by Conjugation to a Tripod Monolayer (5 February 2013)

A new article has been published by T. Alava in the journal, Angewandte Chemie describing a tipodal molecule whose non-covalent functionalization of graphene is superior to direct adsorption of biomolecules. Cells showed enhanced binding and proliferation only on tripodal functionalized graphene by preserving the activity and selectivity of adsorbed antibodies.

Control of the Graphene–Protein Interface Is Required To Preserve Adsorbed Protein Function (31 January 2013)

A new article has been published by T. Alava et al. in the journal,Analytical Chemistry studying the graphene-protein interface and its effect on protein activity. By using a graphene coated QCM, binding strategies of molecules to graphene were monitored and characterized, notably a monolayer of tripod molecules that binds to graphene was shown to preserve the activity of bound proteins.

Approaching intrinsic performance in ultra-thin silicon nitride drum resonators (26 September 2012)

A new article has been published by V. Adiga et al. in the Journal of App Phys. The article observes that the dissipation of silicon nitride drum resonators are dependent on differing factors according to the resonator thickness.

Microfluidic Extraction, Stretching and Analysis of Human Chromosomal DNA from Single Cells (10 September 2012)

A new publication by J. Benitez et al. in Lab-on-a-Chip, demonstrates a device capable of high efficiency DNA extraction from small cell populations for the purposes of either retainment or input into downstream processes.

Photothermal Self-Oscillation and Laser Cooling of Graphene Optomechanical Systems (13 August 2012)

Recent publication by R. Barton et al. in the journal, Nano Letters, explores the photothermal back-action in graphene mechanical resonators as a function of optomechanics.

Ordered Arrays of Native Chromatin Molecules for High-Resolution Imaging and Analysis (21 July 2012)

Congratulations to A. Cerf et al. on the recent article published in ACS Nano, detailing single molecule chromatin combing and labeling capabilities through the process of molecular combing.

Stress-based resonant volatile gas microsensor operated near the critically buckled state (30 May 2012)

A new paper has been published by D. J. Joe et al. in the journal Journal of Applied Physics, describing a method of critically buckled polycrystalline silicon doubly clamped mechanical resonators coated on one side with polymethyl methacrylate (PMMA).

Real-time analysis and selection of methylated DNA by fluorescence-activated single molecule sorting in a nanofluidic channel (3 April 2012)

A new paper has been published by B. R. Cirpriany et al. in the journal Journal of Applied Physics, present a proof-of-principle demonstration for a new method using a nanofluidic device that combines real-time detection and automated sorting of individual molecules based on their epigenetic state.

Synchronous imaging for rapid visualization of complex vibration profiles in electromechanical microresonators (20 Jan 2012)

A new paper has been published by Y. Linzon et al. in the journal Journal of Applied Physics, presenting experimental study of high drive amplitude and ambient pressure effect on the resonant vibration profiles in electrically driven microbridges near critical buckling.

Modal dependence of dissipation in silicon nitride drum resonators (20 Dec 2011)

A new paper has been published by V. P. Adiga et al. in the journal Applied Physics Letters, showing that the dissipation of large diameter high tensile stress SiN membrane mechanical resonators is limited by clamping loss for pure radial modes, but higher order azimuthal modes are limited by a mechanism which appears to be intrinsic to the material.

Single DNA molecule patterning for high-throughput epigenetic mapping (7 Oct 2011)

A new paper has been published by A. Cerf et al. in the journal Analytical Chemistry, presenting a method for profiling the 5-methyl cytosine distribution on single DNA molecules.

Transfer-printing of single DNA molecule arrays on graphene for high-resolution electron imaging and analysis (16 Sept 2011)

A new paper has been published by A. Cerf et al. in the journal Nano Letters, presenting a reliable method for depositing ordered arrays of individual elongated DNA molecules on single-layer graphene substrates for high-resolution electron beam imaging and electron energy loss spectroscopy analysis.

Fabrication and performance of graphene nanoelectromechanical systems (9 Sept 2011)

A new paper has been published by R. A. Barton et al. in the journal Journal of Vacuum Science and Technology B. The article reviews the progress of resonant graphene nanoelectromechanical systems and the possible applications of the technology to signal processing, sensing, and other areas.

An array of planar apertures for near-field fluorescence correlation spectroscopy (6 Apr 2011)

A new paper has been published by C. V. Kelly et al. in the journal Biophysical Journal, showing a method of performing near-field fluorescence correlation spectroscopy to demonstrate the sub-diffraction-limited illumination with an array of planarized circular apertures of 50 nm diameter.

Observing Thermobifida fusca cellulase binding to pretreated wood particles using time-lapse confocal laser scanning microscopy (6 Feb 2011)

A new paper has been published by P. Zhu et al. in the journal Cellulose, reporting on studies of Thermobifida fusca cellulases Cel5A, Cel6B and Cel9A binding to pretreated wood particles using Confocal Laser Scanning Microscopy (CLSM).

High, size-dependent quality factor in an array of graphene mechanical resonators (4 Feb 2011)

A new paper has been published by R. A. Barton et al. in the journal Nano Letters, demonstrating a striking improvement quality factor of circular graphene membrane resonators grown by chemical vapor deposition with increasing diameter.

High-Q nanomechanics via destructive interference of elastic waves (27 Jan 2011)

A new paper has been published by I. Wilson-Rae et al. in the journal Physical Review Letters, showing that for azimuthal harmonics of the circular geometry destructive interference of the radiated waves leads to an exponential suppression of the clamping loss in the harmonic index.

Recent work featured in Technology Review (December 2010)

A recent paper on single-layer graphene resonator arrays has been featured in Technology Review.

Large-scale arrays of single-layer graphene resonators (26 Nov 2010)

A new paper has been published by A. M. van der Zande et al. in the journal Nano Letters, demonstrating that it is possible to produce large arrays of CVD-grown graphene resonators with reproducible properties.

Microfluidic integration of nanomechanical resonators for protein analysis in serum (28 Oct 2010)

A new paper has been published by P. S. Waggoner et al. in the journal Sensors and Actuators B, presenting a technique for reversibly encapsulating nanomechanical resonant sensors within microfluidic channels that are reusable and easy to fabricate.

Honors and Awards from AVS 57th Symposium (27 Oct 2010)

Christine Tan received the Russell and Sigurd Varian Award competitively awarded to a top graduate student for excellence in research and academic record. She also received a Young Investigator Award (Biomaterials Interface Division) awarded to researchers under age 35 for her oral presentation.

Philip Waggoner received the First Prize in the Artzone Competition for his SEM image "Walking the Plank."

Rapid prototyping of nanofluidic systems using size-reduced electrospun nanofibers for biomolecular analysis (27 Sept 2010)

A new paper has been published by S.-m. Park et al. in the journal Small, demonstrating a new method for fabricating nanofluidic systems from size-reduced electrospun nanofibers.

Revisiting the conformation and dynamics of DNA in slitlike confinement (5 Aug 2010)

A new paper has been published by J. Tang et al. in the journal Macromolecules, experimentally investigating the equilibrium conformation and dynamics of single DNA molecules in slitlike nanochannels.

Real-time synchronous imaging of electromechanical resonator mode and equilibrium profiles (1 Aug 2010)

A new paper has been published by Y. Linzon et al. in the journal Optics Letters, showing that profiles of mechanical modes in suspended thin film structures are measured through all-optical Fabry-Perot reflectance fits to the temporal traces.

Atomic layer deposited silicon dioxide films on nanomechanical silicon nitride resonators (2 June 2010)

A new paper has been published by P. S. Waggoner et al. in the journal Journal of Applied Physics, presenting experimental data and an analytical model for the effect of atomic layer deposition (ALD) growth of thin silicon dioxide films deposited on nanomechanical resonators and their effect on the resonant properties of silicon nitride devices as a function of thickness.

Fabrication of a nanomechanical mass sensor containing a nanofluidic channel (5 May 2010)

A new paper has been published by R. A. Barton et al. in the journal Nano Letters, showing the performance of doubly clamped beam resonators that contain filled nanofluidic channels. The resonators operate at frequencies on the order of 25 MHz and when filled with fluid have quality factors as high as 800, two orders of magnitude higher than that of resonators of comparable size and frequency operating in fluid.

Stress-based vapor sensing using resonant microbridges (20 Apr 2010)

A new paper has been published by D. R. Southworth et al. in the journal Applied Physics Letters, demonstrating stress-based sensing of water vapor in ambient pressure nitrogen using doubly clamped buckled beams coated with a hygroscopic polymer.

Surface engineering and patterning using parylene for biological applications (15 Mar 2010)

A new paper has been published by C. P. Tan et al. in the journal Materials. In this article, the emerging role and applications of parylene as a biomaterial for surface chemical modification are reviewed.

Single molecule epigenetic analysis in a nanofluidic channel (25 Feb 2010)

A new paper has been published by B. R. Cipriany et al. in the journal Analytical Chemistry, demostrating a method using nanofluidics and multicolor fluorescence microscopy to detect DNA and histones in individual chromatin fragments at about 10 Mbp/min.

Nanoscale resolution, multicomponent biomolecular arrays generated by aligned printing with parylene peel-off (20 Jan 2010)

A new paper has been published by C. P. Tan et al. in the journal Nano Letters, presenting a high-throughtput method known as "Print-and-Peel" to generate multicomponent biomolecular arrays with sub-100 nm nanoscale feature width.

DNA manipulation, sorting, and mapping in nanofluidic systems (12 Jan 2010)

A new paper has been published by S. L. Levy et al. in the journal Chemical Society Reviews. In this article, recent experiments utilizing fluidic systems comprised of nanochannels, nanoslits, nanopores, and zero-mode waveguides for DNA analysis are reviewed.

Craighead Group News Archive